El artículo: Eschenmoser_1999_Etiol_Nucl_Ac_Structure
Vol. 284 no. 5423 pp. 2118-2124
Chemical Etiology of Nucleic Acid Structure
Systematic chemical studies indicate that the capability of Watson-Crick base-pairing is widespread among potentially natural nucleic acid alternatives taken from RNA’s close structural neighborhood. A comparison of RNA and such alternatives with regard to chemical properties that are fundamental to the biological function of RNA provides chemical facts that may contain clues to RNA’s origin.